m-Chloroperbenzoic acid → HCID 22753324, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1.0 gram (3.26 mmoles) of 2-(4-hydroxyphenyl)-3-benzoyl-6-hydroxybenzothiophene in 50 ml. of ethyl acetate was prepared and cooled to 0° C. The mixture was stirred, and 620 mg. (3.59 mmoles) of m-chloroperbenzoic acid were added. The mixture was stirred for one hour and then was allowed to stand overnight under refrigeration. The product was chromatographed rapidly over silica gel in a fritted glass funnel, elution being carried out with a 7:3 mixture of benzene and ethyl acetate followed by pure ethyl acetate to obtain 220 mg. (19 percent) of the title compound. Mass spectrum: Theory, 362; Found, 362.

Provenance & Evidence