N-Methylhomoveratrylamine → HCID 22752806, compound

HRID 2163527Notes

Reaction equation

HRID 2163527 reaction equation
[CH:1]([C:4]1[C:13]2[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=2)[C:7](=[O:18])[N:6]([CH2:19][CH2:20][CH2:21][Cl:22])[N:5]=1)([CH3:3])[CH3:2].[CH3:23][O:24][C:25]1[CH:26]=[C:27]([CH2:33][CH2:34][NH:35][CH3:36])[CH:28]=[CH:29][C:30]=1[O:31][CH3:32]>ClC1C=CC=CC=1>[ClH:22].[CH:1]([C:4]1[C:13]2[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=2)[C:7](=[O:18])[N:6]([CH2:19][CH2:20][CH2:21][N:35]([CH3:36])[CH2:34][CH2:33][C:27]2[CH:28]=[CH:29][C:30]([O:31][CH3:32])=[C:25]([O:24][CH3:23])[CH:26]=2)[N:5]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 77039N-MethylhomoveratrylamineHCID 22752798HCID 22752798, compound

Product 1

HCID 22752806HCID 22752806, compound

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

1-[4-Isopropyl-6,7-dimethoxy-1(2H)-phthalazinone-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)amino]-propane hydrochloride was prepared analogous to Example 1(b) by reaction of 1-[4-isopropyl-6,7-dimethoxy-1 (2H)-phthalazinone-2-yl]-3-chloro-propane with 3,4-dimethoxyphenylethyl-N-methyl-amine in chlorobenzene. M.p.: 179 - 180° C.

Sources & evidence

ORD record
ord-6e51433bec6943fe846a9e0ee49018d5
Source dataset
uspto-grants-1979_01
Patent number
US04134980

Reaction notes

Loading…