HRID2163537

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID200274

未命名化合物

HCID21584188

Chloroform methanol

C2H5Cl3O

HCID22326631

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(CCN(CCCn2cnc3cc(OC)c(OC)cc3c2=O)Cc2ccccc2)cc1OC

HCID22752803

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID7964

Chlorobenzene

C6H5Cl

PROCEDURE

实验过程

1-(6,7-Dimethoxy-4(3H)-quinazolinone-3-yl)-3-[N-benzyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-amino]-propane was prepared analogous to Example 1 (a) by reaction of 1-(6,7-dimethoxy-4(3H)-quinazolinone-3-yl)-3-chloro-propane with N-(3,4-dimethoxy-phenylethyl)-N-benzyl amine in chlorobenzene. Rf -value (chloroform/methanol = 9.1) : 0.75.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-69c8e44c624b45d3863e3880fe5ed016
来源数据集: uspto-grants-1979_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04134980
来源说明: uspto-grants-1979_01

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[CH:8][N:7]([CH2:15][CH2:16][CH2:17]Cl)[C:6]2=[O:19].[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH2:30][CH2:31][NH:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:25]=[CH:26][C:27]=1[O:28][CH3:29].C(Cl)(Cl)Cl.CO>ClC1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[CH:8][N:7]([CH2:15][CH2:16][CH2:17][N:32]([CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[CH2:31][CH2:30][C:24]1[CH:25]=[CH:26][C:27]([O:28][CH3:29])=[C:22]([O:21][CH3:20])[CH:23]=1)[C:6]2=[O:19]