関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Epichlorohydrin | HCID 7835 | — |
| 反応物 | 4-Hydroxy-2-methylbenzaldehyde | HCID 458185 | — |
| 反応物 | 2-Methyl-4-(2,3-epoxypropyl)benzaldehyde | HCID 20029917 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | 2-Methyl-4-(2,3-epoxypropoxy)benzaldehyde | HCID 13302065 | — |
反応手順
To epichlorohydrin (20 g., 0.216 mole) heated at 55° C. is added dropwise a solution of 2-methyl-4-hydroxybenzaldehyde (9.0 g., 0.066 mole) in 2.5 N sodium hydroxide solution (40 ml.). After the addition, the solution is allowed to stir an additional 3 hours at 55° C. and then at room temperature overnight. The oil is distilled to give 8.3 g. of 2-methyl-4-(2,3-epoxypropyl)benzaldehyde, m.p. 160°-170° C. at 1 mm. Hg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04134983 |
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| 出典データセット | uspto-grants-1979_01 |
|---|
| ORD ID | ord-0a9148e51b374926b6b8edd9e97d77dc |
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| 出典メモ | uspto-grants-1979_01 |
|---|
