Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester → HCID 22750661, compound

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Reaction Steps

39.5 g. of 1-methyl-10,11-dihydro-5-(3-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene are dissolved in 400 ml. of glacial acetic and hydrogenated at room temperature and under normal pressure in the presence of 3 g. of platinum oxide. When the uptake of hydrogen ceases, the catalyst is removed by filtration. The filtrate is evaporated, and the residue distilled whereby 1-methyl-10,11-dihydro-5-(3-dimethylaminopropyl)-5H-dibenzo[a,d]cycloheptene goes over at 140° C. under 0.01 mmHg. The corresponding hydrochloride salt has a melting point of 181°-183° C. after recrystallization from ethanol-ether.

Provenance & Evidence