Dimethylformamide → HCID 70604997, compound

Participants

Reaction Conditions

Reaction Steps

25.1 g (0.1 mole) 2-(5-nitro-furfurylidene)-amino-benzimidazole are stirred in a mixture of 80 ml of dimethylformamide and 120 ml of methyl-ethyl-ketone, whereupon 12.6 g (0.1 mole) cyclohexylisocyanate are added. The reaction mixture is stirred for 6 hours at 40° C. to 45° C., whereupon next day it is cooled to 0° C., filtered off, washed with 20 ml of methyl-ethyl-ketone and dried in vacuo at 40° C. to 60° C. Thus 23 g of 1-cyclohexyl-carbamoyl-2-(5-nitro-furfurylidene)-amino-benzimidazole are obtained. Mp.: 198°-200° C.

Provenance & Evidence