Benzhydrylamine → HCID 178420336, compound

HRID 2163671Notes

Reaction equation

HRID 2163671 reaction equation
[CH:1]([NH2:14])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:16]1[NH:17][CH2:18][CH2:19][N:20]=1>C(OCC)C>[CH:1]([N:14]=[C:16]1[NH:20][CH2:19][CH2:18][NH:17]1)([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7036BenzhydrylamineHCID 2362362-Chloro-4,5-dihydroimidazole

Product 1

HCID 178420336HCID 178420336, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 2.26 g of benzhydrylamine and 30 ml of an ethyl ether solution containing 2.5 g of 2-chloro-2-imidazoline was allowed to stand at room temperature for 2 days. The reaction mixture was then treated in the same manner as in Synthesis Example 1 to give crystals of 2-benzhydryliminoimidazolidine. The crystals were dissolved in methanol and an equivalent amount of concentrated hydrochloric acid solution was added. The solution was distilled off in vacuo to give 3.2 g of 2-benzhydryliminoimidazolidine hydrochloride having a melting point of 207°-209° C.

Workup

  1. additionThe reaction mixture was then treated in the same manner as in Synthesis Example 1

Sources & evidence

ORD record
ord-0f197b69818d4ab9b615e49ba4f7fb36
Source dataset
uspto-grants-1979_01
Patent number
US04136188

Reaction notes

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