HCID 53744655, compound → 3p-Phenoxyphenyl-3-hydroxybutyric acid

HRID 2163699Notes

Reaction equation

HRID 2163699 reaction equation
C([O:3][C:4](=[O:22])[CH2:5][C:6]([C:9]1[CH:14]=[CH:13][C:12]([O:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[CH:11][CH:10]=1)([OH:8])[CH3:7])C>C(O)C>[O:15]([C:12]1[CH:13]=[CH:14][C:9]([C:6]([OH:8])([CH3:7])[CH2:5][C:4]([OH:22])=[O:3])=[CH:10][CH:11]=1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 1

HCID 53744655HCID 53744655, compound

Product 1

HCID 541805473p-Phenoxyphenyl-3-hydroxybutyric acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10 g. of 3-p-phenoxyphenyl-3-hydroxybutyric acid ethyl ester are dissolved in 50 ml. of ethanol and the solution is boiled for 15 minutes with 2 g. of KOH, evaporated and subjected to standard working up to give 3-p-phenoxyphenyl-3-hydroxybutyric acid, m.p. 137°-138°. Cyclohexylamine salt, m.p. 188°-189°.

Workup

  1. customof KOH, evaporated

Sources & evidence

ORD record
ord-f4928514d438429b961c3517aac9de09
Source dataset
uspto-grants-1979_01
Patent number
US04136200

Reaction notes

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