HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-Hydroxy-4-(3-phenoxypropoxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-hydroxy-4-(3-phenoxypropoxy)benzoate | HCID 22751303 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Hydroxy-4-(3-phenoxypropoxy)benzoic acid | HCID 20331437 | 85.3% |
Reaction Steps
A mixture of methyl 2-hydroxy-4-(3-phenoxypropoxy)benzoate (18.55g), methanol (40ml) and 10% aqueous sodium hydroxide (100ml) was stirred at 60° until a clear solution was obtained, then cooled and acidified. The precipitated solid was collected and recrystallised from cyclohexane-ethanol to give 15.09g (85%) of acid of mp 161°. (Found; C, 66.46; H, 5.71; C16H16O5 requires; C, 66.65; H, 5.59%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04136192 |
| Source dataset | uspto-grants-1979_01 |
| ORD ID | ord-7c22c7be0a534c9bb61b377025dc81ac |
| Source note | uspto-grants-1979_01 |