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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2163771Generated: October 25, 2026

Timonacic → 3-[4-(Hexadecylamino)benzoyl]-4-carboxythiazolidine

https://huagongshe.com/reaction/2163771

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTimonacicHCID 9934—
Reactant3-[4-(Hexadecylamino)benzoyl]-4-carboethoxythiazolidineHCID 20437342—
SolventAcetone sodium bicarbonateHCID 86737261—
Product3-[4-(Hexadecylamino)benzoyl]-4-carboxythiazolidineHCID 20437365—

Reaction Steps

By means of the alkaline hydrolysis method of Example 7, the ethyl ester of Example 21 is converted to the subject carboxylic acid. This acid is also prepared using the procedure of Example 21 except that the acylation of the thiazolidine-4-carboxylic acid is carried out in aqueous acetone sodium bicarbonate solution.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04136256
Source datasetuspto-grants-1979_01
ORD IDord-5b11191574bb446b90494df4117a7bc3
Source noteuspto-grants-1979_01