HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phthalimide → N-methyl-N'-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phthalimide | HCID 6809 | — |
| Edukt | Hydrazine | HCID 9321 | — |
| Edukt | Methyl isothiocyanate | HCID 11167 | — |
| Edukt | N-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea | HCID 86736270 | — |
| Produkt | N-methyl-N'-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea | HCID 12923388 | — |
Reaktionsschritte
Treatment of the phthalimide compound (3.0 g.) with hydrazine (1.53 g.) followed by reaction of the product directly with methyl isothiocyanate (0.73 g.) using the conditions described in Example 132 afforded N-methyl)-N-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea (1.0 g.). m.p. 73°-74° (from ethanol-ether-n-hexane).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04137234 |
| Quelldatensatz | uspto-grants-1979_01 |
| ORD ID | ord-62fa46014e2640698d84a9d45967b214 |
| Quellennotiz | uspto-grants-1979_01 |