Ethylamine → N-cyano-N'-ethyl-N"-[2-(3-pyridazinylmethylthio)ethyl]guanidine

HRID 2163965Notes

Reaction equation

HRID 2163965 reaction equation
[CH2:1]([NH2:3])[CH3:2].[C:4]([NH:6][C:7](=[N:10][CH2:11][CH2:12][S:13][CH2:14][C:15]1[N:16]=[N:17][CH:18]=[CH:19][CH:20]=1)SC)#[N:5]>>[C:4]([NH:6][C:7]([NH:3][CH2:1][CH3:2])=[N:10][CH2:11][CH2:12][S:13][CH2:14][C:15]1[N:16]=[N:17][CH:18]=[CH:19][CH:20]=1)#[N:5]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 20567748N-cyano-N'-[2(3-pyridazinylmethylthio)ethyl]-S-methylisothiourea

Product 1

HCID 54546728N-cyano-N'-ethyl-N"-[2-(3-pyridazinylmethylthio)ethyl]guanidine

Procedure

Anhydrous ethylamine is reacted with N-cyano-N'-[2-(3-pyridazinylmethylthio)ethyl]-S-methylisothiourea by the procedure of Example 4 to give N-cyano-N'-ethyl-N"-[2-(3-pyridazinylmethylthio)ethyl]guanidine.

Sources & evidence

ORD record
ord-4c3a9f7e63264c17a6ad69e7237b8548
Source dataset
uspto-grants-1979_01
Patent number
US04137237

Reaction notes

Loading…