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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2163979Generated: October 30, 2026

1,3-Propanediamine → 3-(3-Aminopropylamino)pyridazine

https://huagongshe.com/reaction/2163979

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-PropanediamineHCID 428—
ReactantSodium ethoxideHCID 2723922—
Reactant3-ChloropyridazineHCID 11274989—
SolventEthanolHCID 702—
Product3-(3-Aminopropylamino)pyridazineHCID 18694207—

Reaction Steps

Reacting 3-chloropyridazine with 1,3-diaminopropane in ethanol containing sodium ethoxide according to the procedure of Example 89 gives 3-(3-aminopropylamino)pyridazine. Using this intermediate as the starting material in the procedure of Example 18 gives N-cyano-N'-[3-(3-pyridazinylamino)propyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04137237
Source datasetuspto-grants-1979_01
ORD IDord-d8c44d43277a48ba973ef989e7419e57
Source noteuspto-grants-1979_01