HCID 12412186, compound → HCID 12412188, compound

HRID 2164142Notes

Reaction equation

HRID 2164142 reaction equation
[F:1][C:2]1[CH:19]=[CH:18][C:5]2[S:6][C:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[C:8]([CH2:9][C:10]#[N:11])[C:4]=2[CH:3]=1.[ClH:20].C1(C2SC3C=CC=CC=3C=2CCN)C=CC=CC=1>>[ClH:20].[F:1][C:2]1[CH:19]=[CH:18][C:5]2[S:6][C:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[C:8]([CH2:9][CH2:10][NH2:11])[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 12412186HCID 12412186, compoundHCID 22750367HCID 22750367, compound

Product 1

HCID 12412188HCID 12412188, compound

Procedure

Substitution of an equivalent quantity of 5-fluoro-2-phenylbenzo[b]thiophene-3-acetonitrile for the 2-phenylbenzo[b]thiophene-3-acetonitrile of Example 9 and repetition of the procedure which is described in Example 9 affords 5-fluoro-2-phenylbenzo[b]thiophene-3-ethanamine hydrochloride, melting at 260° C. (decomposition). This compound is represented by the following structural formula. ##STR29##

Sources & evidence

ORD record
ord-22e19917f7164308a88908314cff5905
Source dataset
uspto-grants-1979_01
Patent number
US04137414

Reaction notes

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