6-Chloro-2-phenylpyrimidin-4-amine → HCID 20405987, compound

HRID 2164232Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[C:6](Cl)[N:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1.[CH3:15][O-:16].[Na+]>>[NH2:1][C:2]1[CH:7]=[C:6]([O:16][CH3:15])[N:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1

Participants

Reactant 2

HCID 3177476-Chloro-2-phenylpyrimidin-4-amine

HCID 10942334Sodium Methoxide

Product 1

HCID 20405987HCID 20405987, compound

Procedure

Using the method of Example 33, 4-amino-6-chloro-2-phenylpyrimidine was reacted with sodium methoxide to provide solid 4-amino-6-methoxy-2-phenylpyrimidine. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.

Sources & evidence

ORD record: ord-f4873354017b46349248a2c4adb88c2f
Source dataset: uspto-grants-1985_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04503050

Reaction notes

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