HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 1-(4-Fluorophenyl)-2-(dimethylamino)ethenyl-2-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | (4-Fluorophenyl)acetone | HCID 521187 | — |
| Product | 1-(4-Fluorophenyl)-2-(dimethylamino)ethenyl-2-propanone | HCID 86739957 | — |
Reaction Steps
A mixture of 4-fluorophenyl acetone (50 grams) and 162.5 ml of N,N-dimethylformamide dimethyl acetal in 75 ml of acetonitrile is stirred for 12 hours and then the reaction mixture is concentrated on a rotary evaporator. The residual solid is suspended in 100 ml of hexane and filtered to give 59.6 grams of 1-(4-fluorophenyl)-2-(dimethylamino)ethenyl-2-propanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04503061 |
| Source dataset | uspto-grants-1985_03 |
| ORD ID | ord-fdc42d2a561b4c8a87c58d79d2053582 |
| Source note | uspto-grants-1985_03 |