HCID 13394285, compound → HCID 13394288, compound

Participants

Reaction Steps

A slurry of 27.1 g (0.85 mole) of 5-fluoro-7-(4-fluorobenzoyl)-3-methylthioindolin-2-one in 500 ml of tetrahydrofuran was treated with 220 g of wet Raney nickel. The mixture was filtered and the filtrate was concentrated. The residue obtained was crystallized from acetone to give 14.8 g (64%) of the titled compound as light yellow crystals, m.p. 195°-196.5° C.

Provenance & Evidence