反应详情

A mixture of 25 g (0.09 mol) of p-decyloxybenzoic acid methyl ester and 100 ml of diethylene glycol monomethyl ether was heated for 6 hours to 150° C. with a spatula tip of sodium methanolate. After the excess diethylene glycol monomethyl ether had been distilled off, the residue was taken up in methylene chloride, the solution was washed with water, treated with active carbon and concentrated by evaporation. 24.5 g (72%) of slightly contaminated p-decyloxybenzoic acid 2-(2-methoxyethoxy)-ethyl ester were obtained. Purification by column chromatography (SiO2, Merck/methylene chloride+5% of methanol) produced pure ester having a refractive index nD20 of 1.4945.

1. distillationAfter the excess diethylene glycol monomethyl ether had been distilled off
2. washthe solution was washed with water
3. additiontreated with active carbon
4. concentrationconcentrated by evaporation