3-Ethoxy-4-phenyl-4H-furo[3,2-b]indole-2-carboxamide → 3-Ethoxy-4-phenyl-4H-furo[3,2-b]indole-2-carbonitrile

Participants

Reaction Steps

Prepared by the procedure described in Example 21 from 6.5 g (0.020 mole) of 3-ethoxy-4-phenyl-4H-furo[3,2-b]indole-2-carboxamide. The crude product (5.5 g, 90% yield), after being washed with water and dried, was converted to the corresponding tetrazole without additional purification. A portion of the crude nitrile recrystallized from methanol yielded an analytically pure sample, mp 121°-122° C.

Provenance & Evidence