Butyryl chloride → HCID 20243238, compound

HRID 2164348Notes

Reaction equation

[CH2:1]([C:6]1[C:12]([OH:13])=[CH:11][C:10]([OH:14])=[CH:9][C:7]=1[OH:8])[CH:2]=[C:3]([CH3:5])[CH3:4].[C:15](Cl)(=[O:19])[CH2:16][CH2:17][CH3:18]>>[OH:8][C:7]1[C:9]([C:15](=[O:19])[CH2:16][CH2:17][CH3:18])=[C:10]([OH:14])[C:11]([C:7](=[O:8])[CH2:6][CH2:1][CH3:2])=[C:12]2[C:6]=1[CH2:1][CH2:2][C:3]([CH3:5])([CH3:4])[O:13]2

Participants

Reactant 2

HCID 8855Butyryl chloride

HCID 20243248HCID 20243248, compound

Product 1

HCID 20243238HCID 20243238, compound

Procedure

Phloroglucinol was treated with prenylchloride using the same procedure as described in Example 2 to yield prenylphloroglucinol. Prenylphloroglucinol was treated with butyrylchloride, according to the same procedure as described for the preparation of 2,4-dibutyrylphoroglucinol in Example 34 (Method 2) to yield 5,7-dihydroxy-6,8-dibutyryl-2,2-dimethylchroman (36 after chromatography with silica gel (petroleum ether, ethyl acetate, 4:1).

Workup

customas described for the preparation of 2,4-dibutyrylphoroglucinol in Example 34 (Method 2)

Sources & evidence

ORD record: ord-91f3a6b794734fc98e88b4314759d9ce
Source dataset: uspto-grants-1985_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04503256

Reaction notes

Loading…