Hydroxylamine, O-ethyl- → HCID 135999353, compound

HRID 2164373Notes

Reaction equation

HRID 2164373 reaction equation
[OH:1][C:2]1[CH2:7][CH:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)[CH2:5][C:4](=[O:16])[C:3]=1[C:17](=O)[CH2:18][CH3:19].[CH2:21]([O:23][NH2:24])[CH3:22]>C(O)C>[CH2:21]([O:23][N:24]=[C:17]([C:3]1[C:4](=[O:16])[CH2:5][CH:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)[CH2:7][C:2]=1[OH:1])[CH2:18][CH3:19])[CH3:22]

Participants

4

Reactant 2

HCID 69357Hydroxylamine, O-ethyl-HCID 178458883HCID 178458883, compound

Product 1

HCID 135999353HCID 135999353, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Into 20 ml of ethanol was dissolved 2.9 g of 3-hydroxy-5-(4-methylthiophenyl)-2-propionyl-2-cyclohexen-1-one and to the solution was added 0.8 g of ethoxyamine. The mixture was kept for 15 hours at room temperature and it was poured into ice water. The crystal sedimented was collected with a filtering step and recrystallized with methanol. Thus, 3.1 g of colorless objective crystals having a melting point of 83°-84° C. was obtained.

Workup

  1. customThe crystal sedimented was collected with a filtering step
  2. customrecrystallized with methanol
  3. customwas obtained

Sources & evidence

ORD record
ord-1066c6af41754dda9bc55c726b9a78fe
Source dataset
uspto-grants-1985_03
Patent number
US04504305

Reaction notes

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