O-Allylhydroxylamine → HCID 136436410, compound

HRID 2164374Notes

Reaction equation

HRID 2164374 reaction equation
[C:1]([C:6]1[C:7](=[O:21])[CH2:8][CH:9]([C:13]2[CH:18]=[CH:17][C:16]([S:19][CH3:20])=[CH:15][CH:14]=2)[CH2:10][C:11]=1[OH:12])(=O)[CH2:2][CH2:3][CH3:4].[CH2:22]([O:25][NH2:26])[CH:23]=[CH2:24]>C(O)C>[CH2:22]([O:25][N:26]=[C:1]([C:6]1[C:7](=[O:21])[CH2:8][CH:9]([C:13]2[CH:18]=[CH:17][C:16]([S:19][CH3:20])=[CH:15][CH:14]=2)[CH2:10][C:11]=1[OH:12])[CH2:2][CH2:3][CH3:4])[CH:23]=[CH2:24]

Participants

4

Reactant 2

HCID 420841O-AllylhydroxylamineHCID 178450333HCID 178450333, compound

Product 1

HCID 136436410HCID 136436410, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Into 20 ml of ethanol was dissolved 1.5 g of 2-butyryl-3-hydroxy-5-(4-methylthiophenyl)-2-cyclohexen-1-one and to the solution was added 0.5 g of allyloxyamine. The mixture was kept for 15 hours at room temperature and it was poured into ice water. The crystal sedimented was collected with a filtering step and recrystallized with methanol. Thus, 1.4 g of colorless objective crystals having a melting point of 72°-74° C. was obtained.

Workup

  1. customThe crystal sedimented was collected with a filtering step
  2. customrecrystallized with methanol
  3. customwas obtained

Sources & evidence

ORD record
ord-43ee2e73e2f74ee2a047583a6c8d62a3
Source dataset
uspto-grants-1985_03
Patent number
US04504305

Reaction notes

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