Hydroxylamine, O-ethyl- → HCID 136056365, compound

HRID 2164375Notes

Reaction equation

HRID 2164375 reaction equation
[C:1]([C:6]1[C:7](=[O:22])[CH2:8][CH:9]([C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH3:21])=[O:20])=[CH:15][CH:14]=2)[CH2:10][C:11]=1[OH:12])(=O)[CH2:2][CH2:3][CH3:4].[CH2:23]([O:25][NH2:26])[CH3:24]>C(O)C>[CH2:23]([O:25][N:26]=[C:1]([C:6]1[C:7](=[O:22])[CH2:8][CH:9]([C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH3:21])=[O:20])=[CH:15][CH:14]=2)[CH2:10][C:11]=1[OH:12])[CH2:2][CH2:3][CH3:4])[CH3:24]

Participants

4

Reactant 2

HCID 69357Hydroxylamine, O-ethyl-HCID 178450334HCID 178450334, compound

Product 1

HCID 136056365HCID 136056365, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Into 20 ml of ethanol was dissolved 1.6 g of 2-butyryl-3-hydroxy-5-(4-methylsulfinylphenyl)-2-cyclohexen-1-one and to the solution was added 0.5 g of ethoxyamine. The mixture was kept for 15 hours at room temperature and it was poured into ice water. The crystal sedimented was collected with a filtering step and recrystallized with methanol. Thus, 1.3 g of colorless objective crystals having a melting point of 72°-74° C. was obtained.

Workup

  1. customThe crystal sedimented was collected with a filtering step
  2. customrecrystallized with methanol
  3. customwas obtained

Sources & evidence

ORD record
ord-78ffc28eccd54a36abd968af878f3e4d
Source dataset
uspto-grants-1985_03
Patent number
US04504305

Reaction notes

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