反应详情

33.7 g of 5-phenoxysulfonyl-2-ureidonitrobenzene in 250 ml of methanol and 250 ml of 2-methoxyethanol are hydrogenated under normal pressure with a catalytic amount of Raney nickel. After uptake of hydrogen is complete, the catalyst is filtered off with suction, washed with dimethylformamide and the solution is evaporated under reduced pressure, induced to crystallize with methanol, and the crystals are filtered off with suction and washed with methanol, melting point 180° C., decomposition.

1. filtrationthe catalyst is filtered off with suction
2. washwashed with dimethylformamide
3. customthe solution is evaporated under reduced pressure
4. customto crystallize with methanol
5. filtrationthe crystals are filtered off with suction
6. washwashed with methanol, melting point 180° C., decomposition.