Sulfuric Acid → 2-(3-Acetylureido)-5-phenoxysulfonylnitrobenzene

Participants

Reaction Steps

1 ml of concentrated sulfuric acid is added, with stirring, to 50.5 g of 5-phenoxysulfonyl-2-ureidonitrobenzene in 250 ml of acetic anhydride. A clear solution is produced, followed rapidly by precipitation. The mixture is stirred for a further two hours, and the solid is filtered off with suction and washed consecutively with glacial acetic acid and diisopropyl ether, melting point 198° C., decomposition.

Provenance & Evidence