反应详情

48 g of 2-(3-acetylureido)-5-phenoxysulfonylnitrobenzene in 300 ml of methanol and 300 ml of 2-methoxyethanol are hydrogenated under normal pressure with a catalytic amount of Raney nickel. After hydrogen uptake is complete, the catalyst is filtered off with suction, washed with dimethylformamide and the solution is evaporated under reduced pressure. The residue is stirred with hot methanol, and the solid is filtered off cold under suction and washed with methanol and diisopropyl ether, melting point 202° C., decomposition.

1. filtrationthe catalyst is filtered off with suction
2. washwashed with dimethylformamide
3. customthe solution is evaporated under reduced pressure
4. filtrationthe solid is filtered off cold under suction
5. washwashed with methanol and diisopropyl ether, melting point 202° C., decomposition.