Benzoic acid, 2-chloro-5-(chlorosulfonyl)- → HCID 13705955, compound

HRID 2164554Notes

Reaction equation

HRID 2164554 reaction equation
[CH:1]1([NH:7][S:8]([C:11]2[CH:22]=[C:15]3[C:16]([O:18]C(=O)[NH:20][C:14]3=[CH:13][CH:12]=2)=[O:17])(=[O:10])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:23]C1C=CC(S(Cl)(=O)=O)=CC=1C(O)=O>>[Cl:23][C:14]1[CH:13]=[CH:12][C:11]([S:8](=[O:10])(=[O:9])[NH:7][CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:22][C:15]=1[C:16]([OH:18])=[O:17].[CH:1]1([NH:7][S:8]([C:11]2[CH:22]=[C:15]([C:16]([OH:18])=[O:17])[C:14]([NH2:20])=[CH:13][CH:12]=2)(=[O:10])=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 67306Benzoic acid, 2-chloro-5-(chlorosulfonyl)-HCID 53931880HCID 53931880, compound

Product 2

HCID 13705955HCID 13705955, compoundHCID 20404894HCID 20404894, compound

Procedure

5-(N-Cyclohexylsulfamoyl)-isatoic anhydride, which is to be used as the starting material, can be obtained, for example, in a manner analogous to that described in Example 1, using 2-chloro-5-chlorosulfonylbenzoic acid as the starting material, the product being obtained via 2-chloro-5-(N-cyclohexylsulfamoyl)-benzoic acid with a melting point of 168°-175° and 5-(N-cyclohexylsulfamoyl)-anthranilic acid with a melting point of 204°-206°. It melts at 232°-233°.

Sources & evidence

ORD record
ord-65ce55217962462d90e975f5791fe678
Source dataset
uspto-grants-1985_03
Patent number
US04505913

Reaction notes

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