HCID 600389, compound → 19506-18-4

HRID 2164657Notes

Reaction equation

HRID 2164657 reaction equation
C[O:2][C:3]1[CH:12]=[CH:11][C:10]([O:13]C)=[C:9]2[C:4]=1[N:5]=[CH:6][CH:7]=[N:8]2.[Cl-].[Al+3].[Cl-].[Cl-]>C1C=CC=CC=1>[OH:13][C:10]1[CH:11]=[CH:12][C:3]([OH:2])=[C:4]2[C:9]=1[N:8]=[CH:7][CH:6]=[N:5]2

Participants

4

Reactant 2

HCID 600389HCID 600389, compoundHCID 6451240Aluminum(III) Chloride

Product 1

HCID 13569739619506-18-4Yield 71%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4 g (0.021 mol) of 5,8-dimethoxyquinoxaline was refluxed for 2 hours under heating in 50 ml of benzene together with 20 g of aluminum chloride. After allowing to cool to room temperature, the reaction solution was extracted with ethyl acetate, and the extract was dried and concentrated. Recrystallization of the residue from ethyl acetate gave 2.4 g (71%) of the end product. m.p. 234°-236° C.

Workup

  1. extractionthe reaction solution was extracted with ethyl acetate
  2. customthe extract was dried
  3. concentrationconcentrated
  4. customRecrystallization of the residue from ethyl acetate

Sources & evidence

ORD record
ord-0486eac9e00d4128b2775f52815d369e
Source dataset
uspto-grants-1985_03
Patent number
US04506001

Reaction notes

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