8-Chloro-2,3-dimethylimidazo[1,2-a]pyrazine → 8-Phenylmethoxy-2,3-dimethylimidazo[1,2-a]pyrazine

HRID 2164737Notes

Reaction equation

HRID 2164737 reaction equation
Cl[C:2]1[C:3]2[N:4]([C:8]([CH3:12])=[C:9]([CH3:11])[N:10]=2)[CH:5]=[CH:6][N:7]=1.[C:13]1([CH2:19][O-:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[Na+]>>[C:13]1([CH2:19][O:20][C:2]2[C:3]3[N:4]([C:8]([CH3:12])=[C:9]([CH3:11])[N:10]=3)[CH:5]=[CH:6][N:7]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 107499238-Chloro-2,3-dimethylimidazo[1,2-a]pyrazineHCID 23676753Sodium benzyloxide

Product 1

HCID 108008678-Phenylmethoxy-2,3-dimethylimidazo[1,2-a]pyrazine

Procedure

For example, treating 8-chloro-2,3-dimethylimidazo[1,2-a]pyrazine with sodium phenylmethoxide yields an 8-phenylmethoxy-2,3-dimethylimidazo[1,2-a]pyrazine as shown in rection Scheme V. ##STR17##

Sources & evidence

ORD record
ord-80a6731e4b4042bbb22fe59323b3e500
Source dataset
uspto-grants-1985_03
Patent number
US04507294

Reaction notes

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