HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carbaldehyde → 1-[6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazol-5-yl]-2-methoxy-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carbaldehyde | HCID 11245608 | — |
| Reactant | HCID 178506880 | HCID 178506880 | — |
| Product | 1-[6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazol-5-yl]-2-methoxy-ethanone | HCID 10237875 | — |
Reaction Steps
1-[6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazol-5-yl]-2-methoxy-ethanone 10p is prepared from 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carbaldehyde 10f and lithiomethyl methyl ether by the procedures described in Example 44. MS APCI (+) m/z 412, 414 (M+, Br pattern) detected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193229B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-776bbfffc93f40d7a8a74482a428524e |
| Source note | uspto-grants-2012_06 |