Palmitoyl chloride → HCID 15006861, compound

Participants

Reaction Steps

83.8 g (0.2 mol) of 1,4-diethoxy-2-hexadecanoylaminobenzene prepared from 2,5-diethoxyaniline and hexadecanoyl chloride was dissolved in 500 ml of chloroform and to the solution was added dropwise 100 g of boron tribromide at a temperature range between 5° C. and 10° C. After stirring at room temperature for 6 hours, 50 g of ice and 100 ml of water were added to the mixture and chloroform was distilled off under a reduced pressure. To the residue was added 100 ml of methanol, the resulting precipitate was collected by filtration to obtain 78 g of 2-hexadecanoylaminohydroquinone.

Provenance & Evidence