1-Ethyl-2-methyl-1H-indole-3-carbaldehyde → 1H-Indole, 1-ethyl-2-methyl-

HRID 2164901Notes

Reaction equation

HRID 2164901 reaction equation
C1(C)C=CC(S([O-])=O)=CC=1.[Na+].[CH2:12]([N:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16](C=O)=[C:15]1[CH3:25])[CH3:13]>>[CH2:12]([N:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[C:15]1[CH3:25])[CH3:13]

Participants

3

Reactant 2

HCID 9565841-Ethyl-2-methyl-1H-indole-3-carbaldehydeHCID 2723791Sodium p-toluenesulfinate

Product 1

HCID 1704321H-Indole, 1-ethyl-2-methyl-

Procedure

Following a procedure similar to that described in Example 4A but employing 6.5 g. of 85.9% sodium p-toluenesulfinate 4.6 g. of 1-ethyl-2-methyl-1H-indole-3-carboxaldehyde and 3.8 g. of 1-ethyl-2-methyl-1H-indole there was obtained 4.5 g. of 3-[(1-ehtyl-2-methyl-1H-indol-3-yl)(4-methylphenylsulfonyl)methyl]-1-ethyl-2-methyl-1H-indole, m.p. 146°-152° C.

Sources & evidence

ORD record
ord-5a1fc76fc1934d11ae10928dc42dafb9
Source dataset
uspto-grants-1985_03
Patent number
US04507483

Reaction notes

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