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HRID2164926

反应详情

EQUATION

反应方程式

HRID 2164926 的结构方程式

REACTANTS

反应物

1
结构：CCCc1c(OCCCOc2c(C(C)=O)ccc(OCCCC(=O)OCC)c2CCC)ccc(C(C)=O)c1O
HCID15623025

未命名化合物

PRODUCTS

生成物

1
结构：CCCc1c(OCCCOc2c(C(C)=O)ccc(OCCCC(=O)O)c2CCC)ccc(C(C)=O)c1O
HCID13389156

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CO
溶剂HCID887

Methanol

CH4O

结构：[Na+].[OH-]
溶剂HCID14798

Sodium Hydroxide

HNaO

PROCEDURE

实验过程

A solution of 6.22 g of 4-[4-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]-2-propylphenoxy]butanoic acid ethyl ester in 100 ml of methanol and 57 ml of 1N sodium hydroxide was stirred at reflux for 2 hours. The solvent was removed in vacuo and the pH of the residue was adjusted to 2.0 with 6N hydrochloric acid. The solid was filtered and dried to give 5.16 g (87%), mp 96°-99°, 4-[4-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]-2-propylphenoxy]butanoic acid.

WORKUP

后处理

  1. temperatureat reflux for 2 hours
  2. customThe solvent was removed in vacuo
  3. filtrationThe solid was filtered
  4. customdried