HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 131714176, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 1,3-Dibromopropane | HCID 8001 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2-(4-acetyl-3-hydroxy-2-propylphenoxy)propanoate | HCID 14330021 | — |
| Product | HCID 131714176 | HCID 131714176 | — |
Reaction Steps
A mixture of 6.4 g of racemic-(4-acetyl-3-hydroxy-2-propylphenoxy)-alphamethylacetic acid ethyl ester, 22 ml of 1,3-dibromopropane and 4.5 g of anhydrous potassium carbonate in 175 ml of anhydrous acetone was stirred at reflux for 52 hours. The reaction mixture was filtered and the filtrate was concentrated in vacuo to 9.0 g of racemic-[4-acetyl-3-(3-bromopropoxy)-2-propylphenoxy]methylacetic acid as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04507498 |
| Source dataset | uspto-grants-1985_03 |
| ORD ID | ord-8f196625d5e3487085556e75f058703c |
| Source note | uspto-grants-1985_03 |