HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethoxy-2-methyl-2-propenal → (5-Methylpyrimidin-2-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethoxy-2-methyl-2-propenal | HCID 559198 | — |
| Reactant | 2-Hydroxy-acetamidine hydrochloride | HCID 12217366 | — |
| Product | (5-Methylpyrimidin-2-yl)methanol | HCID 23043337 | — |
Reaction Steps
2-Hydroxymethyl-5-methylpyrimidine was prepared by the reaction of 3-ethoxy-2-methyl acrolein and hydroxyacetamidine hydrochloride following a similar procedure to that described by Kim and McKee (J. Org. Chem., 35, 455 (1970)). Proton magnetic resonance spectrum (CDCl3 ; δ in ppm): 2.32 (3H,s); 3.6 (1H,bs); 4.80 (2H,s); 8.54 (2H,s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04938793 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-f1267336107b431d914a2bb7a88c6b97 |
| Source note | uspto-grants-1990_07 |