Water → Benzenesulfonyl chloride, 4-chloro-3-nitro-

Participants

Reaction Steps

To a solution mixture of 1,280 g of potassium 4-chloro-3-nitrobenzenesulfonate in 1,150 ml of acetonitrile, 250 ml of sulfolane and 30 ml of dimethylacetamide was added dropwise 1,250 ml of phosphorus oxychloride while the temperature was kept at 60° to 70° C. After the reaction proceeded for 3 hours at 73° C., the reaction mixture was cooled with water, then 400 ml of water was added thereto gradually, and then 5 liters of ice water was poured into the reaction mixture. The deposited crystals were filtered followed by washing with water and drying.

Provenance & Evidence