1,3-Dibromobutane → HCID 15067928, compound

HRID 2165050Notes

Reaction equation

HRID 2165050 reaction equation
P([O:4][PH:5]([OH:7])=[O:6])(O)=O.C([C:11]([CH:18]([CH3:20])C)([CH:15]([CH3:17])C)C(C)C)(C)C.BrCCC(Br)C>>[CH3:17][CH:15]1[CH2:11][CH2:18][C:20]1([P:5]([OH:4])(=[O:6])[OH:7])[P:5]([OH:7])(=[O:4])[OH:6]

Participants

3

Reactant 2

HCID 78891,3-DibromobutaneHCID 178443211HCID 178443211, compound

Product 1

HCID 15067928HCID 15067928, compound

Procedure

Using the procedure of Example I, tetraisopropyl methane diphosphonate was converted to tetraisopropyl 2-methyl cyclobutane-1,1 diphosphonate by reaction with 1,3 dibromobutane at 80° C. for 4 hours. 31P NMR (CDCl3) chemical shift 24.1 ppm.

Sources & evidence

ORD record
ord-5ddb2603f8bd47509ec48e5d6eb10a2e
Source dataset
uspto-grants-1990_07
Patent number
US04939131

Reaction notes

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