反应详情

To a solution of 1-(2-benzothiazolyl)ethanol (2.5 g) prepared according to J. Indian Chem. Soc., 566 (1974) in methylene chloride (50 ml) was added thionyl chloride (3.32 g) and the resulting solution stirred at room temperature for 1 hour. The solution was poured onto ice-water (100 ml) and the organic extract separated. This extract was washed with aqueous bicarbonate (10 ml of a 5% solution) and then with water (50 ml). The methylene chloride layer was dried over anhydrous magnesium sulfate and evaporated to a light yellow oil (2.08 g).

1. additionThe solution was poured onto ice-water (100 ml)
2. extractionthe organic extract
3. customseparated
4. washThis extract was washed with aqueous bicarbonate (10 ml of a 5% solution) and then with water (50 ml)
5. dry with materialThe methylene chloride layer was dried over anhydrous magnesium sulfate
6. customevaporated to a light yellow oil (2.08 g)