Methanesulfonyl chloride → HCID 14810655, compound

Participants

Reaction Conditions

Reaction Steps

To an ice-cold solution of 1-(5-trifluoromethyl-2-benzothiazolyl)ethanol (m.p. 93°-94° C., 4.94 g) in dry pyridine was added methanesulfonyl chloride (4.58 g) and the resulting solution stirred at 0° C. for 1 hour. It was poured onto water, extracted with ether and the ether layer washed with 10% hydrochloric acid (2×20 ml). The organic extract was dried, evaporated and the residue triturated with hexane to obtain the desired compound as solid, m.p. 89° C. (5.89 g).

Provenance & Evidence