HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → HCID 23043602, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | 4-(3,4-Dimethoxyphenethyl)aniline | HCID 14256024 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 23043602 | HCID 23043602 | 99.1% |
Reaction Steps
The 4-[2-(3,4-dimethoxyphenyl)ethyl]benzenamine (9.9 g, 38.9 mmole) is dissolved in toluene (125 ml) containing formic acid (5.0 g, 108 mole) and refluxed for one hour. The reaction mixture is cooled to room temperature and evaporated to dryness. Recrystallization of the residue from toluene affords 11.0 g (82%) of N-formyl-4-[2-(3,4-dimethoxyphenyl)ethyl]benzenamine, mp 128°-130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04939133 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-ebbbf7dd02954680b01bbadaeb4a5e81 |
| Source note | uspto-grants-1990_07 |