7-(1,1-Dimethylethyl)-2,3-benzofurandione → HCID 23043620, compound

HRID 2165102Notes

Reaction equation

HRID 2165102 reaction equation
[CH3:1][C:2]([C:5]1[C:13]2[O:12][C:11](=[O:14])[C:10](=[O:15])[C:9]=2[CH:8]=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH2:26][CH2:27][C:28]2[CH:33]=[CH:32][C:31]([NH2:34])=[CH:30][CH:29]=2)[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]>ClCCl>[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH2:26][CH2:27][C:28]2[CH:29]=[CH:30][C:31]([NH:34][C:11](=[O:14])[C:10](=[O:15])[C:9]3[CH:8]=[CH:7][CH:6]=[C:5]([C:2]([CH3:4])([CH3:3])[CH3:1])[C:13]=3[OH:12])=[CH:32][CH:33]=2)[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]

Participants

4

Reactant 2

HCID 122942517-(1,1-Dimethylethyl)-2,3-benzofurandioneHCID 142560244-(3,4-Dimethoxyphenethyl)aniline

Product 1

HCID 23043620HCID 23043620, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 7-(1,1-dimethylethyl)-2,3-benzofurandione (1.0 g, 5 mmol) and 4-[2-(3,4-dimethoxyphenyl)ethyl]benzenamine (1.0 g, 4 mmol) in 10 ml of dichloromethane is stirred at room temperature for 48 hours. The solvent is evaporated and the residue crystallized from ether/hexane. Recrystallization from acetonitrile gave the pure product, (1.0 g) mp 143°-144° C.

Workup

  1. customThe solvent is evaporated
  2. customthe residue crystallized from ether/hexane
  3. customRecrystallization from acetonitrile
  4. customgave the pure product, (1.0 g) mp 143°-144° C.

Sources & evidence

ORD record
ord-6829ea3438db41e099418e4702b7b03b
Source dataset
uspto-grants-1990_07
Patent number
US04939133

Reaction notes

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