HCID 15056951, compound → HCID 15056952, compound

Participants

Reaction Steps

To a solution of 5 (7.77 g, 20.4 mmol) in 80 mL of anhydrous THF at 0°-5° C. was added portionwise LAH (0.97 g, 25.6 mmol). The mixture was stirred for 1.5 h, quenched with 1 mL of H2O, 1 mL of 15% NaOH and 3 mL of H2O and filtered. The volatiles were removed in vacuo and the residue recrystallized with hexanes:EtOAc. Wt. 5.55 g. mp 128°-129° C. Anal. C19H25FOS2 ; Theory C: 64.74; H: 7.15; S:18.19. Found C:. 64.57; H: 7.03; S: 17.71.

Provenance & Evidence