HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl O-acetoacetyl-N-trifluoroacetyl-L-serinate → O-acetoacetyl-N-trifloroacetyl-L-serine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl O-acetoacetyl-N-trifluoroacetyl-L-serinate | HCID 53948101 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | O-acetoacetyl-N-trifloroacetyl-L-serine | HCID 18640001 | 95.4% |
Reaction Steps
A mixture of benzyl O-acetoacetyl-N-trifluoroacetyl-L-serinate (320 mg) and 10% palladium on activated carbon (40 mg) in ethanol (10 ml) was hydrogenated under hydrogen at one atom for 20 minutes. The mixture was filtered with Celite (filter aid, trade mark, made by Nakarai Chemicals) and the filtrate was concentrated to give O-acetoacetyl-N-trifloroacetyl-L-serine (232 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04939241 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-4c02b58b79d64e88a2ff0a6eecbabd51 |
| Source note | uspto-grants-1990_07 |