Chloroacetic Acid → HCID 54537848, compound

HRID 2165238Notes

Reaction equation

HRID 2165238 reaction equation
[NH2:1][C@H:2]([C:6]([O:8][CH2:9][C@@H:10]([C:18]([OH:20])=[O:19])[NH:11][C:12](=[O:17])[C:13]([F:16])([F:15])[F:14])=[O:7])[C@@H:3]([CH3:5])[OH:4].ClCC(O)=O.[N:26]([O-])=O.[K+]>>[N+:1](=[C:2]([C@H:3]([OH:4])[CH3:5])[C:6]([O:8][CH2:9][C@@H:10]([C:18]([OH:20])=[O:19])[NH:11][C:12](=[O:17])[C:13]([F:16])([F:15])[F:14])=[O:7])=[N-:26]

Participants

4

Reactant 3

HCID 300Chloroacetic AcidHCID 516910Potassium nitriteHCID 14357550HCID 14357550, compound

Product 1

HCID 54537848HCID 54537848, compound

Procedure

To a solution of O-(L-threonyl)-N-(trifluoroacetyl)-L-serine (109 mg) were added aqueous 4M chloroacetic acid (20 μl) and aqueous 6M potassium nitrite (120 μl) and the solution was stirred at room temperature for 15 minutes.

Sources & evidence

ORD record
ord-0f5b78629d254967a035d79a7f60ae14
Source dataset
uspto-grants-1990_07
Patent number
US04939241

Reaction notes

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