反应详情

To a solution of platinum (II) potassium chloride, (12.2 g) in water (800 ml) is added (3RS)-3-aminopyrrolidine (2.5 g), and the mixture is stirred at room temperature for 19 hours. The precipitated solid is removed by filtration, and the filtrate is concentrated under reduced pressure. To the residue is added a small amount of water, and the resulting crystals are separated by filtration and washed with water and acetone to give cis-dichloro-(3RS)-3-aminopyrrolidine platinum (II) (6.9 g) as pale yellow crystal.

1. customThe precipitated solid is removed by filtration
2. concentrationthe filtrate is concentrated under reduced pressure
3. additionTo the residue is added a small amount of water
4. customthe resulting crystals are separated by filtration
5. washwashed with water and acetone