Nitric Acid → HCID 54688855, compound

HRID 2165261Notes

Reaction equation

HRID 2165261 reaction equation
[CH2:1]([C:3]1[NH:8][C:7](=[O:9])[CH:6]=[C:5]([OH:10])[CH:4]=1)[CH3:2].[N+:11]([O-])([OH:13])=[O:12]>O>[CH2:1]([C:3]1[NH:8][C:7](=[O:9])[C:6]([N+:11]([O-:13])=[O:12])=[C:5]([OH:10])[CH:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 54688856HCID 54688856, compound

Product 1

HCID 54688855HCID 54688855, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
65 °C

Procedure

20 g (0.145 mol) of 6-ethyl-4-hydroxy-1-H-2pyridone are suspended in 60 ml of 65% strength HNO3 and heated to 65° C. The strongly exothermic reaction is kept under control by cooling with ice. After the reaction subsides, 120 ml of water are added and the mixture is cooled with ice. After 30 minutes, the precipitate is filtered off with suction and dried.

Workup

  1. customThe strongly exothermic reaction
  2. temperatureby cooling with ice
  3. additionare added
  4. temperaturethe mixture is cooled with ice
  5. filtrationthe precipitate is filtered off with suction
  6. customdried

Sources & evidence

ORD record
ord-f4d347dfa6c54abe85abaa270b355fcf
Source dataset
uspto-grants-1990_07
Patent number
US04939262

Reaction notes

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