反应详情

10.5 g of (3S-trans)-3-(t-Butyloxycarbonylamino)-1-benzyloxy-4-methyl-2-azetidinone was dissolved in 250 ml of methanol and hydrogenated with 1.43 g of palladium on carbon (10%) as the catalyst. After 45 minutes the catalyst was filtered off and the filtrate was evaporated in vacuo. The crystalline title compound was dried (vacuum desiccator) at room temperature yielding 7.3 g of the title compound, melting point 161°-162° C., dec.

1. filtrationAfter 45 minutes the catalyst was filtered off
2. customthe filtrate was evaporated in vacuo
3. dry with materialThe crystalline title compound was dried (vacuum desiccator) at room temperature