Tosylmethyl isocyanide → Hexane isopropyl acetate

Participants

Reaction Steps

5-{5-[2,6-Dimethyl-4-(5-oxazolyl)phenoxy]pentyl}-3-methylisoxazole [I; Het=4-(5-oxazolyl), R=CH3, R1 =2-CH3, R2 =6-CH3, R3 =H, X=O, Y=(CH2)5 ] was prepared from 3,5-dimethyl-4-[5-(3-methyl-5-isoxazolyl)pentyloxy]benzaldehyde and tosylmethyl isocyanide according to the procedure of Example 96(b), and was obtained in 69% yield as a pale yellow powder, m.p. 56°-58° C. (from isopropyl acetate-hexane).

Provenance & Evidence