Ethyl 2-oxocyclohexylacetate → HCID 17913401, compound

HRID 2165583Notes

Reaction equation

HRID 2165583 reaction equation
Cl.[Cl:2][C:3]1[CH:19]=[CH:18][C:6]([CH2:7][N:8]([C:10]2[CH:15]=[CH:14][C:13]([S:16][CH3:17])=[CH:12][CH:11]=2)N)=[CH:5][CH:4]=1.[CH3:20][CH2:21][O:22][C:23]([CH2:25][CH:26]1[C:31](=O)[CH2:30][CH2:29][CH2:28][CH2:27]1)=[O:24]>>[Cl:2][C:3]1[CH:19]=[CH:18][C:6]([CH2:7][N:8]2[C:27]3[CH:26]([CH2:25][C:23]([O:22][CH2:21][CH3:20])=[O:24])[CH2:31][CH2:30][CH2:29][C:28]=3[C:15]3[C:10]2=[CH:11][CH:12]=[C:13]([S:16][CH3:17])[CH:14]=3)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 91229Ethyl 2-oxocyclohexylacetateHCID 67867375HCID 67867375, compound

Product 1

HCID 17913401HCID 17913401, compound

Procedure

Following the procedure of Example 1, but using 1-(4-chlorobenzyl)-1-(4-methylthiophenyl) hydrazine hydrochloride and ethyl 2-cyclohexanone acetate as starting materials, the title compound was prepared as a mixture of ethyl and isopropyl esters. The pure title compound was obtained by purification on a flash chromatogram.

Sources & evidence

ORD record
ord-334ee600785d4022ae0ac0db63607db7
Source dataset
uspto-grants-1990_07
Patent number
US04940719

Reaction notes

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