Ethyl 2-oxocyclohexylacetate → 9-p-Chlorobenzyl-8-methylthio-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid, methyl ester

HRID 2165587Notes

Reaction equation

HRID 2165587 reaction equation
[ClH:1].[CH3:2][S:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10]N.C[CH2:13][O:14][C:15]([CH2:17][CH:18]1[C:23](=O)[CH2:22][CH2:21][CH2:20][CH2:19]1)=[O:16]>>[Cl:1][C:21]1[CH:22]=[CH:23][C:18]([CH2:17][N:10]2[C:23]3[CH:18]([CH2:17][C:15]([O:14][CH3:13])=[O:16])[CH2:19][CH2:20][CH2:21][C:22]=3[C:6]3[C:5]2=[C:4]([S:3][CH3:2])[CH:9]=[CH:8][CH:7]=3)=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 91229Ethyl 2-oxocyclohexylacetateHCID 21952754[2-(Methylsulfanyl)phenyl]hydrazine hydrochloride

Product 1

HCID 1317164649-p-Chlorobenzyl-8-methylthio-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid, methyl ester

Procedure

Following the procedure of Example 30, but using 1-(2-methylthiophenyl) hydrazine hydrochloride and ethyl 2-cyclohexanone acetate as starting materials, the title compound was prepared.

Sources & evidence

ORD record
ord-c8acbbd6ccb64595919b182e845636b8
Source dataset
uspto-grants-1990_07
Patent number
US04940719

Reaction notes

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